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notch signaling inhibitor dapt  (TargetMol)


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    TargetMol notch signaling inhibitor dapt
    Notch Signaling Inhibitor Dapt, supplied by TargetMol, used in various techniques. Bioz Stars score: 93/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/notch signaling inhibitor dapt/product/TargetMol
    Average 93 stars, based on 2 article reviews
    notch signaling inhibitor dapt - by Bioz Stars, 2026-03
    93/100 stars

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    Notch signaling pathway is required for Ajuba (JUB)-induced chemoresistance. (a) Protein levels of JUB and Notch1 (NICD) in the indicated cells. (b) Colony number in the indicated groups. (c) Sphere number in the indicated groups. Data are presented as the mean ± standard deviation SD values of three independent experiments; n = 3, ** P < 0.01, *** P < 0.001. (GADPH: Glyceraldehyde-3-phosphate dehydrogenase, JUB: Ajuba, DAPT: Notch signaling inhibitor gamma-secretase inhibitor, 5-FU: 5-Fluorouracil)

    Journal: CytoJournal

    Article Title: Targeting the Ajuba/Notch axis increases the sensitivity of colon cancer cells to 5-fluorouracil

    doi: 10.25259/Cytojournal_44_2024

    Figure Lengend Snippet: Notch signaling pathway is required for Ajuba (JUB)-induced chemoresistance. (a) Protein levels of JUB and Notch1 (NICD) in the indicated cells. (b) Colony number in the indicated groups. (c) Sphere number in the indicated groups. Data are presented as the mean ± standard deviation SD values of three independent experiments; n = 3, ** P < 0.01, *** P < 0.001. (GADPH: Glyceraldehyde-3-phosphate dehydrogenase, JUB: Ajuba, DAPT: Notch signaling inhibitor gamma-secretase inhibitor, 5-FU: 5-Fluorouracil)

    Article Snippet: The cells were first treated with the Notch signaling inhibitor gamma-secretase inhibitor (DAPT, 10uM, Selleck, S2215), which could remarkably reduce the expression of Notch1 but did not affect the protein level of JUB [ ].

    Techniques: Standard Deviation